Human and Non-Human Primate Cell Atlas: Publication Package Highlights (Oct 26, 2023)
The human brain contains more than 100 billion cells, but exactly how these cells are organized into types and how these cell types differ between brain regions and species is an open question.
This webinar presents a new collection of studies focused on defining and characterizing the underlying gene expression, gene regulatory, and morphoelectric features of cell types in the human and non-human primate (NHP) brain. These studies employ a range of cellular resolution methods (most notably single cell genomics) for this purpose, marking the beginning of an exciting new era of high-resolution human and NHP analyses. The implications for understanding of human brain function, disease and disease modeling are profound.
More about the collection of studies:
Speakers:
Ed Lein, Allen Institute for Brain Science 1:18
Kimberly Siletti, University Medical Center Utrecht, Netherlands, 5:12
“Transcriptomic diversity of cell types in the adult human brain”
Trygve Bakken, Allen Institute for Brain Science, 13:45
“Comparative transcriptomics reveals human-specific cortical features”
Lijuan Liu, Southeast University, China, 22:40
“Whole Human-Brain Mapping of Single Cortical Neurons for Profiling Morphological Diversity and Stereotypy”
Wei Tian, Salk Institute, 32:17
” Epigenomic complexity of the human brain revealed by single-cell DNA methylomes and 3D genome structures”
Chang Kim, University of California, San Francisco, 41:42
“Spatiotemporal molecular dynamics of the developing human thalamus”
Q&A: 51:32
Moderator: Yasmeen Hussain, Allen Institute for Brain Science
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